Anise Seed for Fungus

Anise Seed (pimpinella asisum) is a native plant of Greece and Egypt and is probably the oldest known aromatic seed. Anise Seed is a gray-brown oval seed from Pimpinella anisum, a plant in the parsley family. Anise has a licorice-like taste and commercially it is used to scent perfumes and soaps and to flavor toothpastes and mouthwashes. Because of this, it is commonly used in baking and cooking as well as in some alcoholic beverages such as the Greek Ouzo.

Anise has been recognized and used since the seventh century, B.C. In biblical times, taxes were often paid in Anise Seeds. The Romans widely cultivated Anise for its fragrance, flavor and health properties. Early American Colonists used it as an expectorant, to assist digestion, fight infections, promote milk production, and improve indications of menopause. Anise seed was also used to vitalize the immune system and stimulate digestion. It is related to Caraway, Dill, Cumin, and Fennel. The genus name Pimpinella is thought to be derived from the Latin “bipinnula”, or bipinnate, as the leaves are arranged symmetrically on both sides. Chemically anise is similar to fennel, however its constituents are more powerful against harmful organisms and fungus.

The chemical constituents in anise include essential oil (anethole, estragol, methyl chavicol), furano- coumarins, flavonoid glycosides, fatty acids, phytoestrogens, starch, protein, choline, mucilage (see list below for detailed description of chemical constituents). It has been shown in research that the addition of anise seed to other fungal cleansing formulas increases the effectiveness. For example, when Anise was added to Horopito pepper it increased the effectiveness against candida (yeast infection) by 32 times!

Mycozil contains ACTIVE HORPITO and Anise in the exact ratio that was used in this study, making it a very powerful combination product against nail fungus, toenail fungus, candida, yeast infection, athlete’s foot and other fungal infections. Below are a couple of recent research abstracts that demonstrate the effectiveness of anise against the fungus Aspergillus parasiticus (very dangerous fungus that causes the condition known as Aspergilliosis) and as an insecticide.

Chemical Constituents in Anise (aka Aniseed; Pimpinella anisum):

Note: Phenols are marked with an asterisk

cis-Anethole* (0.31%)
trans-Anethole* (91.75%)
Anisaldehyde* (0.63%)
Benzene, 1-trans-propenyl-2-(2′-methyl)butyrate-5-methoxy* (1.42%)
para-Cymene (0.01%)
Estragole* (1.18%)
Limonene (0.01%)
Sesquiterpene hydrocarbon (Structure unavailable) (2.17%)
g -Terpinene (0.01%)
Source: Essential Oils Analysis
Anise seed, green aniseed (seeds)
g -Himachalene (structure unavailable)
Anisol (Anise alcohol)
Isochavibetol (structure unavailable)
cis-Anethole (>0.03%)
trans-Anethole (>96%)
Estragole (Chavicol methylether) (>1%)
Anisaldehyde (Anisic aldehyde, 4-methoxybenzaldehyde)
Anis-ketone (p-methoxyphenylacetone)
Coumarins (linked structure is coumarin itself)
Furocoumarins (structure unavailable)
Source: The Aromatherapy Practitioner Reference Manual

Research Abstracts

J of MedFood, Summer 2005
Effect of spice hydrosols on the growth of Aspergillus parasiticus NRRL 2999 strain.
Ozcan M.
Department of Food Engineering, Faculty of Agriculture, Selcuk University, Konya, Turkey.

The inhibitory effects of 16 spice hydrosols [anise, basil, cumin, dill, Aegean sage, fennel (sweet), laurel, mint, oregano, pickling herb, rosemary, sage, savory, sea fennel, sumac, and thyme (black)] on the mycelial growth of Aspergillus parasiticus strain NRRL 2999 were investigated in vitro. The hydrosols of anise, cumin, fennel, mint, pickling herb, oregano, savory, and thyme showed a stronger inhibitory effect on mycelial growth, while sumac, sea fennel, rosemary, sage, Aegean sage, laurel, basil, and rosemary hydrosols were unable to inhibit totally the growth. Of these, sumac had the least effect on the mycelial growth of A. parasiticus. The effectiveness of the inhibitors followed the sequence anise = cumin = fennel = mint = pickling herb = oregano = savory = thyme > laurel > dill > sage > rosemary > basil > sea fennel > rosemary > sumac.

This abstract of research done in 2004 showed that the chemical p-anisaldehyde was more effective than the common insecticide DEET against dust mites. Read below-

Planta Med. 2004 Mar;70(3):279-81. Related Articles, Links

p-Anisaldehyde: acaricidal component of Pimpinella anisum seed oil against the house dust mites Dermatophagoides farinae and Dermatophagoides pteronyssinus.

Lee HS.

Research Center for Industrial Development of Biofood Materials and Institute of Agricultural Science & Technology, College of Agriculture, Chonbuk National University, Chonju, South Korea.

The acaricidal activity of anise seed oil-derived p-anisaldehyde and commercially available components of anise seed oil was examined against Dermatophagoides farinae and D. pteronyssinus and compared with those of the synthetic acaricides, benzyl benzoate and N,N-diethyl- m-toluamide (DEET). On the basis of LD 50 values, the compound most toxic to D. farinae adults was p-anisaldehyde (1.11 microg/cm2) followed by benzyl benzoate (9.32 microg/cm2), DEET (36.84 microg/cm2), 3-carene (42.10 microg/cm2), and estragol (43.23 microg/cm2). Against D. pteronyssinus adults, p-anisaldehyde (0.98 microg/cm2) was much more effective than benzyl benzoate (6.54 microg/cm2), DEET (17.79 microg/cm2), 3-carene (39.84 microg/cm 2), and estragol (40.11 microg/cm2). p-Anisaldehyde was about 8.4 and 6.7 times more toxic than benzyl benzoate against D. farinae and D. pteronyssinus adults, respectively. The results suggested that p-anisaldehyde may be useful as a lead compound for the development of new agents for the selective control of house dust mites.

Abstracts were reprinted with permission from PubMed

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